Rabies is a deadly disease transmitted through the bite or scratch of an infected animal, most commonly dogs. This disease attacks the central nervous system and, if not treated promptly and properly, is almost always fatal.

Anti-Rabies Serum (SAR), also known as Rabies Immunoglobulin (RIG), is a type of passive immunization used in the treatment of patients who have been bitten, scratched, or are at risk of being infected by the rabies virus. SAR is a crucial part of the Post-Exposure Prophylaxis (PEP) protocol, which is the preventive treatment after rabies exposure.

When Is SAR Given?

SAR should be administered immediately after someone is bitten or scratched by an animal suspected of having rabies, especially if:

• The wound is classified as severe (Category III by WHO), such as deep bites, bleeding scratches, or injuries near the head and neck.
• The patient has never received a rabies vaccine.
• The animal cannot be captured or its vaccination status is unknown.

Types of SAR Available

• HRIG (Human Rabies Immunoglobulin): Derived from human plasma, this type is considered safer and has minimal side effects.
• ERIG (Equine Rabies Immunoglobulin): Derived from horse serum, it is more affordable but carries a higher risk of allergic reactions in some patients.

At several healthcare facilities, including Sanur Medical Clinic, HRIG is available to ensure optimal safety and effectiveness for patients.

SAR Must Be Combined with Rabies Vaccine

SAR is not administered on its own. According to WHO’s rabies prophylaxis protocol, SAR must be combined with the rabies vaccine as part of the post-exposure treatment. The serum provides immediate passive immunity, while the vaccine helps the body develop long-term protection against the virus.

Sanur Medical Clinic Provides Human Rabies Immunoglobulin (HRIG)

For optimal safety and effectiveness, Sanur Medical Clinic offers HRIG (Human Rabies Immunoglobulin) as part of our rabies post-exposure treatment.

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Sumber Referensi:

• WHO. Rabies. 2022. https://www.who.int/ith/vaccines/rabies/en/
• Kementerian Kesehatan RI. (2022). Pedoman Pengendalian Rabies.
• CDC. (2020). Rabies Post-Exposure Prophylaxis (PEP). https://www.cdc.gov/rabies/medical_care
• Rabies immune globulin, human Pregnancy and Breastfeeding Warnings. 2022. https://www.drugs.com/pregnancy/rabies-immune-globulin-human.html